| Application Dept. |
Graduate Institute of Biomedical Engineering |
| Principal Investigator |
A.P. Shu-Ping Lin ( Personal Webpage ) |
| Project Title |
Development of Breast Cancer Cell-Based Biosensor Platform for Monitoring Functional Nanocarriers as Drug Delivery System |
| Co-Principal Investigator |
1. Prof. Chih-Feng Huang, Dept. Chemical Engineering 2. A.P. Yi-Chun Chen, Dept. Forestry |
| Co-Investigator |
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| Abstract |
With the rapid emerging research of nanotechnology and polymer engineering in biomedical applications, scientists start to develop state-of-the-art diverse biosensing platforms. Here, we applied nano/micro electromechanical systems to fabricate nano/micro biosensors for developing an in-vitro cell-based biosensors (CBB) in the detection of electrophysiological changes after drug treatment for human breast cancer cells. The green process is applied to transfer biomass into bio-monomers for further synthesizing drug-embedded nanocarriers. With the help of CBB platform, the real-time electrical signals can be applied to monitor the therapeutic efficacy of the nanocarriers assisted drug delivery system and screening large libraries of potential drugs for cancer treatment. |
