| Application Dept. |
Institute of Biomedical Engineering |
| Principal Investigator |
Prof. Hui-Min David Wang |
| Project Title |
A fast estimation platform of anticancer drugs for personal precision medicine by using double reaction hydrogel droplet and dielectrophoretic separation technique |
| Co-Principal Investigator |
Prof. Ching-Chou Wu, Dept. of Bio-industrial Mechatronics Engineering |
| Co-Investigator |
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| Abstract |
This project used a liquid bead microfluidic system to conduct three-dimensional culture of skin cancer cells, combined with lane design and dielectrophrosis (DEP) control to establish a cell sorting platform that does not require antibody calibration and fluorescence scattering interpretation systems, and is applied to the rapid screening of cancer substances in skin cancer cells (B16F10) is helpful to the promotion of personalized precision medicine. Before clinicians start a complete course of treatment, by taking advantage of the drug response of hydrogel three-dimensional cultured bionic cells and the advantage of the low sample volume of the liquid bead microfluidic system, a small amount of cancer cells can be obtained from cancer patients for drug screening. Anti-cancer drugs that are beneficial to the treatment of individual patients will greatly reduce the uncertainty and time/money cost of current drug treatment, and increase the patient′s chance of cure. |
