Flexible Bioimpedance Sensor for Detection of Cell Viability Application of High Throughput Analysis
- Publication Date: 2019-12-23
| Execution Methods |  |
| Performance Evaluation | 1. Successfully developed a flexible sensor and impedance analyzer. 2. Successfully established the regression relationship between cell impedance and phase angle and cell survival rate. |
| Conclusion & Suggestion | High throughput screening is based on cell culture in microplates, with the aid of automatic operational system, rapid and sensitive detection methods, and rapid interpretation of measured data for a rapid screening of drug or medical materials. This project has successfully developed a system, consisted of flexible sensor and impedance analyzer. The flexible sensor, highly manufacture feasible and low-cost, fabricated by screen printing process containing a total of eight gold electrodes. The system measures the cell impedance value in a microplate and to develop a sensing that can be placed in a microplate by optimizing the regression relationship with the cell survival rate and frequency. The device can be applied to suspension cells, microorganisms and plant cells, and for prompt screening of drugs. In the future, the results will be used to apply for drug-industry cooperation cases with pharmaceutical companies. |
| Appendix |