| Execution Methods |
In combination of materials synthesis and physics, as well as biotechnology, this interdisciplinary team aims to develop a novel composite structure which can achieves high SERS activity. This SERS substrate comprises hollow oxide sphere and muliti-shell layers with different functions. It can be suspended in solution, well reacted with analytes, and reusable. Modified with specific antibody, the proposed SERS substrate successfully detects breast cancer cells. |
| Performance Evaluation |
- This interdisciplinary team successfully developed the proposed SERS substrate. Anti-RAGE protein of breast cancer cells can be effectively detected using this novel composite. This is an efficient and inexpensive way to detect breast cancer tumor.
- Our team has submitted two proposals to MOST. One was rejected, and the other one is still under review.
- Our team is now preparing several manuscripts based on the relevant results. One has been published in Nanoscale, and another one has been submitted to Applied Surface Science. (see the appendix)
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| Conclusion & Suggestion |
- In combination of materials synthesis and physics, as well as biotechnology, this interdisciplinary team successfully developed highly active SERS substrate for cancer tumor detection. The proposed hollow composite structure exhibits additional advantages of high buoyancy, magnetic controllability and reusability. The developed novel SERS substrate has great potential for practical application.
- We will further extend the applications and search for more funding support.
- We will promote this technique, for say, attend technical and innovative contests.
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| Appendix |
Appendix 1 |
