Application Dept. |
Graduate Institute of Biomedical Engineering |
Principal Investigator |
A.P. Chian-Hui Lai ( Personal Webpage ) |
Project Title |
Development of a therapeutic nano-platform specifically activated by bacteria-dual-response antibiotic-loaded nanoparticles |
Co-Principal Investigator |
Prof. Wei-Li Hsu, G. I. of Microbiology and Public Health |
Co-Investigator |
|
Abstract |
We aim to synthesis a polymeric nanoparticle form by the self-assemble behavior of carbohydrate and boronic acid-grafted copolymer. The particle structure would be stable due to the complex formation from the copolymer. The nanoplatform is expected to address the antimicrobial resistant (AMR) disease via anti-adhesion therapy and specific delivery of bactericidal drugs. |